Whisky production in Scotland can be divided into the following zones: The Highlands, Speyside (a small coastal section of the northeastern Highlands,) Campbeltown, Islay, The Islands of Arran, Jura, Mull, Orkney, Raasay and Skye, and The Lowlands.
The Lowlands are located in southern Scotland and are named as such for the flatter plains between the mountainous Highlands and the border of England. Given this location, The Lowlands have always been more industrialized and urban and the face of Scotland, with Edinburgh (less than 2 hours by rail from Newcastle), Glasgow, Dundee, and Aberdeen as its main cities.
As far as Scotch is concerned, The Lowlands produce just a fraction of Whisky made in the Highlands and Speyside. There are fewer than 20 Lowland distilleries, the most famous of which are Auchentoshan, Bladnoch, and Glenkinchie. If you're beginning to explore Scotch Whisky, look to the Lowlands for their smooth, light, sweet, and floral drams. You won't find too much peat, smoke, saline, or iodine here.